Chem. Pharm. Bull. 53(9) 1077—1082 (2005)
نویسندگان
چکیده
great physiological and biological activities which is further exemplified by their roles as anticoagulants (dicoumarols/ warfarins), aflatoxins and psoaralens, the important drugs in use. Apart from the above, their role as caging agents in photoactivable “caged” analogues of biomolecules, cytidine diphosphate and glutamic acid, and as probes for reactive oxygen species (ROS) spurred further interest in these compounds. Earlier studies from our laboratory on biological activity of coumarins and their complexes, showed significant enhancement of antibacterial and antifungal activity of the coumarin derivative on complexation. Keeping this in mind, and in continuation of our previous studies, in the present contribution we report the synthesis and characterisation of Ln(III) complexes with a potentially quadridentate ligand, 3-acetylcoumarin-o-aminobenzoylhydrazone (ACAB) and effect of complexation on biological activity of this ligand.
منابع مشابه
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